OSAS and Overweight
A weight loss of at least 10 kg over one year provides a significant reduction in the number of episodes of obstructive sleep apnea in obese patients with diabetes type 2 and the OSA.
The journal Minerva “has previously published an analysis of screening Syndrome Obstructive Sleep Apnea (OSA) and the efficiency of delivery of continuous positive air pressure (CPAP) on daytime sleepiness in patients with this syndrome . Weight reduction is often recommended in cases of OSAS, but clinical evidence of the effectiveness of this weight loss are lacking. A recent observational study shows that 86% of obese patients a type 2 diabetes have OSAS.
Clinical research section which follows this observation includes 264 patients with type 2 diabetes, mean age of 61.2 ± 6.5 years with an average weight of 102.4 ± 18.3 kg (BMI of 36 , 7 ± 5.7) and apnea hypopnea index (AHI) of 23.2 ± 16.5, divided into 2 groups.
The first received standard care for diabetic education (control group) and the second intervention of intensive lifestyle including severely restricting caloric intake based on body weight associated with at least 175 minutes of exercise per week. After a year, AHI was reduced from 5.4 (SD 1.5) in the intervention group and increased 4.2 (SD 1.4) in the control group (p <0.001 for difference).
This difference is mainly due to a decrease in the number of apnea episodes in the intervention group, which also allows remission up to 3 times more common in OSAS.A link was observed between the decrease in AHI and weight loss (-10.8 ± 0.7 kg in the intervention group vs. -0.6 ± 0.7 kg in the control group). A weight loss of at least 10 kg is necessary to observe a significant difference in AHI between the 2 groups. This study provides a sufficient level of proof because of the large number of patients included (men and women) and the long observation period. His results, however, can not be extrapolated to non-diabetic subjects and younger patients with OSAS or considered mild (AHI from 5.0 to 14.9 per hour).
Analysis: A randomized study is The Effect of weight loss is obstructive sleep apnea Among obese patients with type 2 diabetes.
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Tags: apnea, osas, overweight, sleep, sleep apnea